WeWontRegain — The Journal https://wewontregain.com/journal Essays on the science, the strategy, and the lived experience of the 18 months after stopping a GLP-1. en-us The Maintenance Dose Question: What 2026 Research Says About Tapered Off vs. Microdose https://wewontregain.com/journal/maintenance-dose-question https://wewontregain.com/journal/maintenance-dose-question Tue, 19 May 2026 09:00:00 GMT STEP-Maintain and TIDE-2 are testing ultra-low maintenance dosing — and reshaping what a successful exit looks like. Why Bone Density Loss Is the Quiet Cost of GLP-1 Treatment https://wewontregain.com/journal/bone-density-quiet-cost https://wewontregain.com/journal/bone-density-quiet-cost Mon, 18 May 2026 09:00:00 GMT 2026 DEXA cohort data documenting BMD loss most acute in perimenopausal women. The Microbiome Reset: What Happens to Your Gut After Stopping Ozempic https://wewontregain.com/journal/microbiome-reset-after-ozempic https://wewontregain.com/journal/microbiome-reset-after-ozempic Sat, 16 May 2026 09:00:00 GMT 2026 metagenomics studies mapping how GLP-1s reshape the gut microbiome and what reverts post-discontinuation. Food Noise Has a Brain Signature: fMRI Studies and the Rebound https://wewontregain.com/journal/food-noise-brain-signature https://wewontregain.com/journal/food-noise-brain-signature Fri, 15 May 2026 09:00:00 GMT 2026 neuroimaging studies have mapped exactly which brain regions go quiet on GLP-1s — and which re-activate during the rebound. The Compounded Semaglutide Crackdown — What 2026 Means for Women Forced Off https://wewontregain.com/journal/compounded-semaglutide-crackdown https://wewontregain.com/journal/compounded-semaglutide-crackdown Thu, 14 May 2026 09:00:00 GMT FDA enforcement is reshaping the compounded GLP-1 market. The regulatory landscape and what to do. Cardiovascular Benefits That Stay (And the Ones That Don't): SELECT Follow-up Data https://wewontregain.com/journal/cardiovascular-benefits-durability https://wewontregain.com/journal/cardiovascular-benefits-durability Wed, 13 May 2026 09:00:00 GMT SELECT trial follow-up data shows which cardiovascular benefits persist after discontinuation. Why the Mediterranean Diet Specifically Reduces Post-GLP-1 Regain https://wewontregain.com/journal/mediterranean-diet-post-glp1 https://wewontregain.com/journal/mediterranean-diet-post-glp1 Mon, 11 May 2026 09:00:00 GMT MEDI-MAINT compared four dietary patterns in post-GLP-1 maintenance. The Mediterranean pattern outperformed. The Retatrutide Question: What the Triple-Agonist Trials Mean Today https://wewontregain.com/journal/retatrutide-triple-agonist https://wewontregain.com/journal/retatrutide-triple-agonist Sat, 09 May 2026 09:00:00 GMT Retatrutide and the next generation of obesity drugs are 12-24 months from FDA approval. Sleep Architecture After Ozempic: 2026 Polysomnography Findings https://wewontregain.com/journal/sleep-architecture-after-ozempic https://wewontregain.com/journal/sleep-architecture-after-ozempic Thu, 07 May 2026 09:00:00 GMT First polysomnography studies of post-GLP-1 sleep are revealing substantial changes most clinicians don't track. Pharmacogenomics and Your Personal Regain Risk: First Predictive Markers https://wewontregain.com/journal/pharmacogenomics-regain-risk https://wewontregain.com/journal/pharmacogenomics-regain-risk Tue, 05 May 2026 09:00:00 GMT 2026 research is identifying the first genetic markers that predict who maintains GLP-1 weight loss and who regains. What Happens to Your Body the First 30 Days After Stopping Ozempic https://wewontregain.com/journal/first-30-days-after-stopping-ozempic https://wewontregain.com/journal/first-30-days-after-stopping-ozempic Tue, 12 May 2026 09:00:00 GMT A week-by-week breakdown of the physiological changes that happen in the first month after your last GLP-1 dose. Why You're Hungrier Than Before You Started the Drug https://wewontregain.com/journal/why-youre-hungrier-than-before https://wewontregain.com/journal/why-youre-hungrier-than-before Tue, 05 May 2026 09:00:00 GMT The ghrelin rebound is real, and it's louder than your pre-drug baseline. The 4x Faster Regain: What the Cambridge Study Actually Said https://wewontregain.com/journal/the-4x-faster-regain https://wewontregain.com/journal/the-4x-faster-regain Tue, 28 Apr 2026 09:00:00 GMT Plain-language breakdown of the 2026 meta-analyses on post-GLP-1 weight regain. Why Most Coaches Won't Touch GLP-1 Clients https://wewontregain.com/journal/why-most-coaches-wont-touch-glp1 https://wewontregain.com/journal/why-most-coaches-wont-touch-glp1 Tue, 21 Apr 2026 09:00:00 GMT The coaching industry has been avoiding medicated clients for two years. The Muscle Mass Problem Nobody Warned You About https://wewontregain.com/journal/muscle-mass-problem https://wewontregain.com/journal/muscle-mass-problem Tue, 14 Apr 2026 09:00:00 GMT Up to 40% of GLP-1 weight loss can be lean mass. In perimenopause, it compounds. Tapering vs Quitting Cold Turkey: Which One Is Actually Safer? https://wewontregain.com/journal/taper-vs-cold-turkey https://wewontregain.com/journal/taper-vs-cold-turkey Tue, 07 Apr 2026 09:00:00 GMT Both paths work. The protocol matters more than the exit. Perimenopause + Post-Ozempic: The Double Storm Nobody's Mapping https://wewontregain.com/journal/perimenopause-and-post-ozempic https://wewontregain.com/journal/perimenopause-and-post-ozempic Tue, 31 Mar 2026 09:00:00 GMT Two simultaneous metabolic shifts. Most coaches are trained for only one. The Shame Question: Why You Felt Judged for Taking the Drug https://wewontregain.com/journal/the-shame-question https://wewontregain.com/journal/the-shame-question Tue, 24 Mar 2026 09:00:00 GMT The "easy way out" judgment is a public health issue. What to Eat in the First Week After Your Last Dose https://wewontregain.com/journal/what-to-eat-first-week https://wewontregain.com/journal/what-to-eat-first-week Tue, 17 Mar 2026 09:00:00 GMT Structure beats willpower. The framework for the acute window. The 18-Month Window: Why Year 2 Off the Drug Matters Most https://wewontregain.com/journal/the-18-month-window https://wewontregain.com/journal/the-18-month-window Tue, 10 Mar 2026 09:00:00 GMT 12-week programs aren't designed for an 18-month problem.